Gerardo Martino enjoyed his competitive debut with Barcelona more than Carlos Ancelotti's with Real Madrid as the La Liga champions stormed to a 7-0 rout of Levante in their season opener at the Nou Camp on Sunday.
A depleted Barcelona reached the King's Cup semi-finals with a 6-3 aggregate win over Real Betis despite losing Wednesday's second leg to the second division leaders.
Barcelona suffered a shock 2-1 home defeat by Granada on Thursday, conceding two second-half goals to blow the chance of moving top of La Liga.
Third tier Poli Ejido came from behind to clinch a 3-2 win at home to Espanyol in their King's Cup last-16 first leg on Wednesday.
Real Madrid swatted aside Granada 4-1 on Thursday to ensure the La Liga title race will go down to the wire.
Cristiano Ronaldo ended a barren scoring run in La Liga by striking late to give Real Madrid a 2-1 win at neighbours Getafe on Saturday, preventing what would have been a costly and embarrassing draw for the Spanish and European champions.
Here are five talking points from the weekend in La Liga.
Villarreal continued their impressive revival after a season in the second division when Jeremy Perbet and Jonathan Pereira struck in a 2-1 win at home to Espanyol in La Liga on Thursday.
Atletico Madrid kept pace with leaders Barcelona and restored their five-point lead over third-placed city rivals Real when Diego Costa and David Villa each scored a penalty in a 2-1 win at Granada in La Liga on Thursday.
La Liga leaders Barcelona hit two goals in the final three minutes to earn a 3-2 win at Rayo Vallecano
Atletico Madrid striker Alvaro Morata scored a goal and then missed a penalty as his side began their La Liga campaign with an eventful and nervy 1-0 win at home to Getafe on Sunday which saw both teams reduced to 10 men.
Messi, who has struggled for form in recent weeks due to a niggling injury, looked on a mission to grab the winner and after twice coming close he completed his treble to put Barca ahead in the 85th minute, reacting quickly to a poor Sevilla clearance to dink the ball over goalkeeper Tomas Vaclik.
Morata, who had scored his first goal for the club in last week's 2-0 win over Villarreal, rose to head home from close range on the half-hour mark following a corner which had been flicked on by Atleti captain Diego Godin.
Gijon spoiled Asier Illarramendi's return to Real Sociedad's midfield after rejoining from Real Madrid this week when they held the Basque club, coached by Scot David Moyes, to a 0-0 draw in San Sebastian.
Diego Costa scored twice as Atletico Madrid beat Valencia 3-0 to maintain their winning home run this season and keep pace with Barcelona at the top of the La Liga table.
Barcelona snatched a late 2-1 win at Getafe with Paulinho's strike sending them seven points clear of arch-rivals Real Madrid at the top of La Liga.
News of all that's transpired on and off the football field
The victory saw the unfashionable Madrid club tighten their grip on the coveted fourth spot in the table by moving on to 58 points after 36 games, three points clear of nearest challengers Sevilla, who lost to Leganes on Friday.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field