Jefferson-Wooden's winning time was short of the 10.65 seconds she ran in the US track and field championship at the start of August, but only bettered this year by Olympic champion Julien Alfred of Saint Lucia.
With seven points from Thursday's second-place finish at the Lausanne Diamond League, Neeraj Chopra is joint third alongside Julian Weber in Diamond League standings with 15 points.
World champion Dafne Schippers proved she will be the sprinter to beat over 200 metres at next year's Rio Games with victory over Olympic champion Allyson Felix at the Diamond League athletics finale in Brussels on Friday.
Britain's multiple world and Olympic champion Mo Farah ended a three-year absence from the track in style on Friday when he broke the world record for the one hour run at the Brussels Diamond League athletics meeting.
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