Tottenham Hotspur recorded 13 COVID-19 cases at the club last week, while Leicester City and Manchester United were also affected by the virus.
The win moves Leeds up to third on 10 points, albeit having played an extra game, two points behind Villa, while leaders Everton, who have 13 points, are at Southampton on Sunday.
Marriner also ruled out a goal for the Saints from a quickly-taken free kick just before halftime, saying he had not blown the whistle before James Ward-Prowse played in Che Adams, who put the ball in the net.
Images from Sunday's action in the Premier League
Leeds United's Premier League relegation fears heightened as they slipped to a 2-1 defeat at Aston Villa on Friday, leaving Jesse Marsch's side without a win in their last seven games in all competitions.
IMAGES from the English Premier League matches played on Sunday.
Chelsea remain in fourth place, and are two points off third-placed Leicester City who have a game in hand.
IMAGES from the English Premier League matches played on Saturday.
Images from Tuesday's action in the Premier League
Images from the Premier League matches played on Thursday.
Leicester City's veteran striker Jamie Vardy came off the bench to break his long scoring drought and earn his side a 1-1 draw with a late equaliser
IMAGES from the Premier League matches played on Sunday.
Images from Sunday's action in the Premier League.
'We changed our attitude, desire and organisation at halftime and then we were completely different. It was good for my players to learn and to suffer on the pitch'
Images from Sunday's action in the Premier League.
Salah himself blasted home the spot-kick and Leeds looked as though they may be in for a very long day.
Middlesbrough were rewarded for beating Manchester City with a trip to FA Cup holders Arsenal while Chelsea's conquerors Bradford City host Sunderland or Fulham after the fifth round draw on Monday.
Son Heung-min scored his 100th goal for Tottenham Hotspur as they returned to winning ways with a 3-0 defeat of Leeds United to climb back into the English Premier League's top four on Saturday.
Liverpool's hopes of opening up a menacing five-point lead at the top of the Premier League were scuppered in unlikely fashion as struggling West Bromwich Albion snatched a 1-1 draw at Anfield
Images from the English Premier League matches played on Saturday.
Chelsea, Manchester City and Manchester United enjoyed comfortable wins in the English Premier League on Saturday as fans returned to stadiums after an eight-month absence.
ManchesterCity's hopes of regaining the Premier League title suffered a potentially grievous blow on Saturday as they were held to a goalless draw by struggling NorwichCity at Carrow Road.
A summary of Sunday's action in the Premier League.
Arsenal's inability to kill off the contest will be a frustration as that has been a hallmark of their recent form. They had won their previous 18 Premier League matches in which they scored first.
Manchester City needed a second-half penalty from striker Erling Haaland to break the resistance of a dogged Crystal Palace.
FA Cup added another incredible chapter to its proud heritage on Saturday as Chelsea and Manchester City were humbled by supposed inferiors.
IMAGES from the English Premier League matches played on Sunday.
Ben Johnson and Tomas Soucek scored second-half goals as West Ham United twice came back from a goal down to earn a 2-2 draw at home to Brighton and Hove Albion in the Premier League on Sunday.
Rodriguez whipped Everton in front from the edge of the box, and Michael Keane and Calvert-Lewin ensured it was two wins from two in the Premier League so far this season.
Images from the English Premier League matches played on Saturday.
A round-up of Saturday's action in the Premier League.
A summary of Saturday's action in the Premier League.
Chelsea extended their impressive turnaround under new coach Thomas Tuchel with a 2-0 home win over in-form Everton on Monday as Kai Havertz played a key role in both goals on his return to the starting 11.
Liverpool's Mohamed Salah ended his Premier League goal drought in style by scoring twice as the champions raided the capital again to crush West Ham United 3-1 on Sunday.
Images from the English Premier League matches played on Saturday.
IMAGES from the English Premier League matches played on Saturday.
Brighton & Hove Albion scored three times in the second half to fight back from two goals down and beat Manchester City
Images from English Premier League matches played on Sunday.
Images from the English Premier League matches on Saturday.
Manchester United eased the pressure on manager Ole Gunnar Solskjaer with a 3-1 win at Everton in the Premier League on Saturday with Bruno Fernandes scoring twice and Edinson Cavani grabbing his first for the club.