While Sen needed just 40 minutes to advance Sameer Verma retired hurt against Indonesia's Shesar Hiren Rhustavito at the end of the second game when the scoreline reading 16-21, 21-12 in another men's singles match.
However, it was curtains for former Commonwealth Games champion Parupalli Kashyap after he went down 10-21 19-21 to Denmark's Hans-Kristian Solberg Vittinghus.
World number one Kento Momota was stunned by number 38 South Korea's Heo Kwanghee on Wednesday, going down 15-21, 19-21 and looking visibly despondent at each lost point in his first round match at the Olympics, on Wednesday.
World No 26 Satwik and Ashwini showed their grit as they recovered from a mid-game slump to outwit the sixth seeded Indonesian pair
The prestigious awards recognise the achievements of the elite badminton players
P V Sindhu and Lakshya Sen sailed into the second round but it was curtains for Saina Nehwal and Kidambi Srikanth on a mixed day for India at the French Open Super 750 badminton tournament in Paris on Wednesday.
Srikanth blew two game points in the second game to lose 7-21, 20-22 to Axelsen in the men's singles summit clash.
The 24-year-old from Hyderabad will begin her campaign against China's Li Xuerui, a former Olympic gold medallist and World No 1.
Summary of sports events and persons who made news on Sunday.