Real Madrid coach Zinedine Zidane has tested positive for the coronavirus, the La Liga club said in a statement on Friday.
The French coach was isolating earlier this month after a close contact tested positive for COVID-19 and did not attend a training session as a result.
Zidane, who is under pressure following Real's shock cup defeat to third division side Alcoyano earlier this week, will not be available for their La Liga match away at Alaves on Saturday with his assistant David Bettoni set to take charge.
Real are second in the league standings, seven points behind city rivals Atletico Madrid, who have a game in hand.
Real Madrid forward Eden Hazard, midfielder Casemiro and defender Eder Militao also tested positive earlier this season.
Manchester City striker Sergio Aguero confirmed on Thursday that he has tested positive for COVID-19.
"After a close contact, I've been self-isolating and the latest test I took was positive for COVID 19," he said on Twitter.
"I had some symptoms and I'm following doctor's orders for recovery. Take care, everyone!"
Aguero, City's record scorer, has missed their last four games, including Wednesday's victory over Aston Villa.
"We need Aguero, we miss him. The numbers speak for themselves, the best striker in our history," manager Pep Guardiola said ahead of the Villa game.
City face fourth-tier Cheltenham Town in the FA Cup fourth round this weekend.
