Sixth seed Andy Roddick breezed into the third round with a 6-1, 6-4 win over fellow American Mardy Fish.
The top US player showed no signs of being rusty in his first game of the year on clay, polishing off the first set in 23 minutes.
Fish put up stiffer resistance at the start of the second, producing some thumping forehand winners before Roddick broke in the seventh game of the set.