Leander Paes [Images] and Nenad Zimonjic, seeded sixth, lost to third seeded Mike and Bob Bryan in the men's doubles quarter finals at the French Open on Wednesday.
Paes and Zimonjic were beaten 6-7 (5-7), 3-6 by the American pair.
Earlier, seventh seeds Mahesh Bhupathi [Images] and Lisa Raymond bowled out of the mixed doubles.
The Indo-US pair were shown the door by fourth seeds Anastasia Myskina [Images] of Russia [Images] and Jonas Bjorkman of Sweden, losing 4-6, 2-6 in the quarter-finals.
Sixth seeds Leander Paes of India and Martina Navratilova of the United States take on the United States' Corina Morariu and Jared Palmer in another quarter-final later in the day.