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Dr Reddy's R&D findings to be shown in US

Our Bureau in Hyderabad

Novel drug discovery research findings made by Dr Reddy's research centre at Atlanta, US, have been selected for presentation at the American Heart Association's annual scientific sessions to be held in Chicago from November 17 to November 21.

Dr Reddy's presentation at the sessions, which will host over 10,000 medical scientists, will showcase the role of an intra-cellular signaling protein in uncontrolled smooth muscle proliferation - a process that triggers cardiovascular disorders, including restenosis and atherosclerosis.

The presentation will also highlight the role of the intra-cellular signalling protein in the expression of pro-inflammatory genes, Dr Reddy's said in a release.

Aberrant expression of these genes results in the progression of a number of inflammatory diseases, including arthritis, inflammatory bowel disease, septic shock and asthma, the release added.

Dr Reddy's is currently using these and other propriety findings on this protein to design small organic molecules as potential novel anti-inflammatory and anti-prolferative drugs.

Dr Reddy's Atlanta team uses a genomics-based approach to discover new targets and chemical entities in the areas of atherosclerosis, restenosis, diabetic nephropathy and arthritis, while the drug discovery programme at Hyderabad focuses on cancer, inflammation, bacterial infections and metabolic disorders with emphasis on type-2 diabetes, dyslipidemia and obesity.

Dr Reddy's research pipeline currently has three molecules in clinical development and seven molecules in pre-clinical development.

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