David Goffin proved too hot to handle for Novak Djokovic as the Belgian 10th seed reached the Monte Carlo semi-finals with a thrilling 6-2, 3-6, 7-5 victory on Friday.
Former world number one Djokovic saved four match points but cracked under his opponent's tremendous pressure on the fifth as Goffin set up a last-four meeting with either clay court king Rafael Nadal or Argentine Diego Schwartzman.
Earlier, Spanish clay court specialist Albert Ramos beat Croatian fifth seed Marin Cilic 6-2, 6-7 (5) 6-2.
France's Lucas Pouille made a fast start before being made to work harder by Uruguay's Pablo Cuevas, eventually winning 6-0, 3-6, 7-5.
In the first European clay court tournament of the season, Serbian second seed Djokovic was overwhelmed in a one-sided opening set before playing more patiently in the second, but Goffin put on a gritty display in the decider.
Djokovic was serving at 4-3 but Goffin won the game to love to roar back into contention, taking every opportunity to unsettle the French Open champion.
In the 12th game, Goffin opened a 40-15 lead on Djokovic's serve but the 12-times grand slam champion saved four match points before netting a forehand to lose to the Belgian for the first time in six meetings.
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