After losing only three league games last season Juventus have now lost the first two of the new campaign as a deserved 2-1 defeat at AS Roma on Sunday condemned the champions to their worst-ever Serie A start.
Not since Bologna in 1941 have the champions of Italy begun the defence of their title with successive defeats and Juve, beaten 1-0 at home by Udinese last week, have never previously suffered such a start.
They can have no complaints about Sunday's defeat either as last year's runners-up struck through Miralem Pjanic and Edin Dzeko before Paulo Dybala struck late on for Juventus who finished with 10 men with Patrice Evra having been sent off.
Roma were on top throughout and unlucky not to be ahead at halftime after Pjanic hit a post.
The Bosnian's radar was better calibrated after the hour when he curled home an excellent free kick to put Roma ahead.
Juventus then had defender Evra dismissed for a second booking before another Bosnian Dzeko, newly arrived on a season-long loan from Manchester City, rose well to head the second.
Dybala pulled one back three minutes from time to set up a frantic finale but Juve could not find the equaliser and remain without a point.
Roma move on to four points from two games, trailing early pacesetters Sassuolo who have won their first two matches.
PSG's Cavani on target, Di Maria impressive in Monaco win
It took him some time but when Paris St Germain's Edinson Cavani found his range he netted a second-half double to help snatch a 3-0 win at Monaco that extended the champions' perfect Ligue 1 start on Sunday.
Uruguay striker Cavani was his usual wasteful self in the first half, missing a couple of chances, until he found the net in the 57th and 73rd minutes to put PSG on a maximum 12 points from four games.
Ezequiel Lavezzi added a third seven minutes from time after being perfectly set up by fellow Argentine Angel Di Maria, who was impressive on his debut after joining PSG from Manchester United during the close season.
Laurent Blanc's side lead Stade de Reims by three points while Monaco, who were eliminated in the playoff round of the Champions League by Valencia earlier this week, are 13th on five points.
PSG, who have yet to concede a goal this season, started with Zlatan Ibrahimovic up front as the Sweden striker made his Ligue 1 season debut after recovering from a knee injury, with Di Maria started on the bench.
Cavani sent a header over the bar and miscued a shot on the stroke of halftime as PSG dominated possession but failed to really unsettle a solid Monaco defence.
Cavani eventually opened the scoring with a header at the near post from Blaise Matuidi's cross.
He made it two 16 minutes later with a low shot after being set up by Ibrahimovic.
In the 83rd, PSG put the hammer down when Lavezzi collected Di Maria's defence-splitting pass from his own half before firing past Subasic from inside the box.