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At least 45 people were killed and 273 injured when a massive blast shook the Civil Lines area of Lahore city on Wednesday. The blast occurred in 15 Building adjacent to the Capital City Police Office, where the additional inspector general of police is based. Gunshots were also heard in the area after the explosion that shattered the windowpanes of nearby buildings and destroyed many vehicles. The entire building, described as the provincial headquarters of the Inter-Services Intelligence was said to have collapsed.