Nine people have died and over 100 injured following a head-on collision between two local trains in southern Germany's Bavaria.
Among the casualties, 50 are "seriously injured" according to police.
The head-on crash happened at Bad Aibling, a spa town about 60 km southeast of Munich.
One of the trains was derailed in the crash and several carriages were overturned, German media reported.
"This is the biggest accident we have had in years in this region and we have many emergency doctors, ambulances and helicopters on the scene," police spokesman Stefan Sonntag said.
He said the two regional trains had collided on a single track between Rosenheim and Holzkirchen shortly before 07:00 local time (06:00 GMT or 11.30 am).
German news agency DPA reports that eight rescue helicopters are standing on a lawn near the town's entrance and that more rescue workers are on their way to the scene.
Pictures from the scene show dozens of ambulances lined up on a road nearby.
A journalist for local broadcaster Bayerischer Rundfunk reported that rescuers were climbing on the wreckage and pulling people out.
The rail route was closed to traffic, as well as two local roads.
"The accident is an enormous shock for us," said Bernd Rosenbusch, who heads the Bavarian rail company BOB that operates trains on the route.
"We will do everything to help travellers, their relatives and our employees," he added.